Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23612239 | 0.77 | HTR1D (0.44) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL29988859 | 0.76 | HTR1D (0.43) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL23612170 | 0.76 | HTR1D (0.43) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| SCHEMBL3629976 | 0.75 | HTR2B (0.65) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| Hydrochloric Acid SCHEMBL23612169 | 0.75 | HTR1D (0.42) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| SCHEMBL2736671 | 0.71 | HTR2A (0.56) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| SCHEMBL8628537 | 0.70 | HPGD (0.49) | HTR1DHTR2AHTR2CHTR1ACYP1A2 | |
| SCHEMBL23612158 | 0.67 | HTR2C (0.56) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| SCHEMBL3631962 | 0.67 | GPR84 (0.58) | HTR1DHTR2BHTR2AHTR2CHTR1A | |
| SCHEMBL3624363 | 0.67 | MPO (0.59) | HTR2BHTR2AHTR2CHTR1AGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466251-B | Condensed heterocyclic compound, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-06-21 | — | — | CN | disclosed |