Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2886228 | 0.87 | FFAR1 (0.62) | TDP1L3MBTL1FFAR1FFAR4ALDH1A1 | |
| SCHEMBL2920609 | 0.87 | LMNA (0.61) | TDP1L3MBTL1FFAR1FFAR4PPARG | |
| SCHEMBL10078216 | 0.86 | FFAR1 (0.51) | TDP1L3MBTL1FFAR1FFAR4ALDH1A1 | |
| SCHEMBL2883654 | 0.86 | FFAR1 (0.54) | TDP1L3MBTL1FFAR1FFAR4PPARG | |
| SCHEMBL3036279 | 0.83 | FFAR1 (0.49) | TDP1L3MBTL1FFAR1FFAR4ALDH1A1 | |
| SCHEMBL2886326 | 0.83 | FFAR1 (0.54) | TDP1L3MBTL1FFAR1FFAR4PPARG | |
| SCHEMBL225229 | 0.82 | FFAR1 (0.69) | FFAR1 | |
| SCHEMBL18477944 | 0.80 | TDP1 (0.57) | TDP1L3MBTL1PPARGPPARAPTGES | |
| SCHEMBL13140348 | 0.80 | FFAR1 (0.70) | FFAR1FFAR4ALDH1A1TSHR | |
| SCHEMBL5289682 | 0.80 | TDP1 (0.56) | TDP1L3MBTL1PPARGPPARAPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |