SCHEMBL5289682

SCHEMBL5289682

Cc1ccccc1OCCOc1ccc(C(C)C)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.56
L3MBTL1 Q9Y468 4/20 0.56
DRD2 P14416 2/20 0.54
DRD4 P21917 2/20 0.54
DRD3 P35462 1/20 0.54
CYP2D6 P10635 2/20 0.46
CYP2C19 P33261 2/20 0.46
CYP1A2 P05177 1/20 0.46
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
SCN4A P35499 1/20 0.45
PTGES O14684 1/20 0.44
ALOX5 P09917 1/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 2/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18477944 0.87 TDP1 (0.57) TDP1L3MBTL1DRD2DRD4DRD3
SCHEMBL5289799 0.83 L3MBTL1 (0.59) TDP1L3MBTL1DRD2DRD4DRD3
SCHEMBL3763522 0.82 DRD2 (0.73) TDP1L3MBTL1DRD2DRD4DRD3
SCHEMBL5279270 0.82 DRD2 (0.72) TDP1L3MBTL1DRD2DRD4DRD3
SCHEMBL3764814 0.82 KCNA3 (0.54) MEN1KMT2AMAPTLMNAALDH1A1
SCHEMBL10824702 0.82 KMT2A (0.59) TDP1MEN1KMT2AHTTLMNA
SCHEMBL12301162 0.81 TDP1 (0.69) TDP1L3MBTL1DRD2DRD4DRD3
SCHEMBL8067303 0.81 L3MBTL1 (0.64) TDP1L3MBTL1DRD2DRD4DRD3
SCHEMBL386935 0.81 L3MBTL1 (0.65) TDP1L3MBTL1DRD2DRD4DRD3
SCHEMBL2923463 0.80 TDP1 (0.56) TDP1L3MBTL1DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4659643-A A PHENOXY COMPOUND KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-04-21 US disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed