Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | RAD52 | P43351 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | S100B | P04271 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 3/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864170 | 0.98 | GAA (0.65) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL6223137 | 0.98 | GAA (0.65) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL6273294 | 0.98 | GAA (0.65) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL7032717 | 0.96 | GAA (0.67) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL6266805 | 0.94 | GAA (0.70) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL15358759 | 0.92 | GAA (0.77) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL6151434 | 0.92 | GAA (0.77) | GAARAD52MAPTALDH1A1MEN1 | |
| Sulfuric Acid SCHEMBL6651961 | 0.90 | GAA (0.56) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL5203985 | 0.86 | GAA (0.61) | GAARAD52MAPTALDH1A1MEN1 | |
| SCHEMBL6254071 | 0.85 | GAA (0.55) | GAARAD52MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660982-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20140343098-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-11-20 | — | — | US | disclosed |
| US-20140343098-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-11-20 | — | — | US | disclosed |
| US-20140343098-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-11-20 | — | — | US | disclosed |
| US-8802700-B2 | Modulators of ATP-Binding Cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-12 | — | — | US | disclosed |
| US-8802700-B2 | Modulators of ATP-Binding Cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-12 | — | — | US | disclosed |
| US-8802700-B2 | Modulators of ATP-Binding Cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2014-08-12 | — | — | US | disclosed |
| US-8614327-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-12-24 | — | — | US | disclosed |
| US-20130165442-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-06-27 | — | — | US | disclosed |
| US-20130165442-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2013-06-27 | — | — | US | disclosed |
| EP-0891765-B1 | Oxidative hair dye compositions | P & G CLAIROL INC (US) | 2004-06-16 | — | — | EP | disclosed |
| EP-1348695-A1 | Derivatives of paraphenylene diamine with pyrrolidine groups substituted by cationic radicals and their use for dyeing keratinic fibre | L'OREAL (FR) | 2003-10-01 | — | — | EP | disclosed |
| CN-1407403-A | Colour developing liquid treating agent composition for silver coloured camera photosensitive materials and method thereof | FUJI PHOTO FILM CO LTD (JP) | 2003-04-02 | — | — | CN | disclosed |
| EP-1122598-A2 | Photographic processing composition containig a diaminostilbene derivative and image forming method using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0891765-A3 | Oxidative hair dye compositions | Bristol-Myers Squibb Company (US) | 2000-01-05 | — | — | EP | disclosed |
| EP-0891765-A2 | Oxidative hair dye compositions | Bristol-Myers Squibb Company (US) | 1999-01-20 | — | — | EP | disclosed |
| EP-0891765-A2 | Oxidative hair dye compositions | Bristol-Myers Squibb Company (US) | 1999-01-20 | — | — | EP | disclosed |
| US-5851237-A | Oxidative hair dye compositions and methods containing 1--(4-aminophenyl) pyrrolidines | NOXELL CORPORATION | 1998-12-22 | — | — | US | disclosed |
| US-5851237-A | Oxidative hair dye compositions and methods containing 1--(4-aminophenyl) pyrrolidines | NOXELL CORPORATION | 1998-12-22 | — | — | US | disclosed |
| US-5585378-A | Composition containing an oxoindole compound | AKTIEBOLAGET ASTRA (SE) | 1996-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165442-A1 | Modulators of ATP-Binding Cassette Transporters | CFTR, ABCB1, ABCC2 | GAA 454/4885RAD52 4217/4885MAPT 4269/4885 |
| US-20140343098-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | GAA 454/4885RAD52 4217/4885MAPT 4269/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.