Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | RAD52 | P43351 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | S100B | P04271 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150891 | 0.93 | GAA (0.69) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL519972 | 0.93 | GAA (0.69) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL6151809 | 0.93 | GAA (0.69) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL30191093 | 0.93 | GAA (0.69) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL6266805 | 0.92 | GAA (0.70) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL7032717 | 0.90 | GAA (0.67) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL30565926 | 0.87 | MAPT (0.65) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL3935104 | 0.87 | MAPT (0.65) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL5836840 | 0.86 | GAA (0.47) | GAAMAPTKDM4EPTK2BMAPK1 | |
| SCHEMBL2923577 | 0.86 | GAA (0.67) | GAAMAPTKDM4EPTK2BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | claimed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | claimed |
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | L'OREAL S.A. (FR) | 2005-05-19 | — | — | US | claimed |
| US-9181239-B2 | Pyridopyrimidinone inhibitors of kinases | ABBVIE INC. (US) | 2015-11-10 | — | — | US | disclosed |
| EP-2776434-A1 | PYRIDOPYRIMIDINONE INHIBITORS OF KINASES | Abbvie Inc. (US) | 2014-09-17 | — | — | EP | disclosed |
| US-20130102590-A1 | PYRIDOPYRIMIDINONE INHIBITORS OF KINASES | ABBVIE INC (US) | 2013-04-25 | — | — | US | disclosed |
| WO-2013059485-A1 | PYRIDOPYRIMIDINONE INHIBITORS OF KINASES | ABBVIE INC. (US) | 2013-04-25 | — | — | WO | disclosed |
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | disclosed |
| EP-1417184-B1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | OREAL (FR) | 2007-08-29 | — | — | EP | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-7241317-B2 | Composition for dyeing keratin fibers comprising at least one para-phenylenediamine substituted with a diazacycloheptane radical | L'OREAL, S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| EP-1417184-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014093-A1 | COMPOSITION FOR DYEING KERATINOUS FIBRES CONTAINING A PARAPHENYLENEDIAMINE SUBSTITUTED BY A DIAZACYCLOHEPTANE RADICAL | L'OREAL (FR) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102590-A1 | PYRIDOPYRIMIDINONE INHIBITORS OF KINASES | WEE1, WEE2, CDK1 | GAA 2624/4885MAPT 2447/4885KDM4E 585/4885 |
| US-20050102769-A1 | Composition for dyeing keratinous fibers containing a paraphenylenediamine substituted by a diazacycloheptane radical | KRT18, HPD, PPOX | GAA 4732/4885MAPT 2115/4885KDM4E 1418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.