Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 7/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29235330 | 0.88 | FOLH1 (0.46) | FOLH1ABCB1SLC16A3 | |
| SCHEMBL8012445 | 0.80 | ALDH1A1 (0.52) | FOLH1SLC16A3 | |
| SCHEMBL339041 | 0.79 | FOLH1 (0.54) | FOLH1SLC16A3NPC1MAPTMAPK1 | |
| SCHEMBL8038086 | 0.77 | FOLH1 (0.59) | FOLH1SLC16A3 | |
| SCHEMBL9770470 | 0.76 | SLC16A3 (0.48) | FOLH1SLC16A3 | |
| SCHEMBL9770477 | 0.76 | SLC16A3 (0.48) | FOLH1SLC16A3 | |
| SCHEMBL27589955 | 0.76 | FOLH1 (0.46) | FOLH1SLC16A3TSHR | |
| SCHEMBL466585 | 0.76 | SLC16A3 (0.53) | FOLH1SLC16A3 | |
| SCHEMBL1042260 | 0.76 | SLC16A3 (0.53) | FOLH1SLC16A3 | |
| SCHEMBL480252 | 0.76 | SLC16A3 (0.53) | FOLH1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | disclosed |