Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.58 |
| ▸ | HTR7 | P34969 | 9/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29507805 | 0.94 | HTR1A (0.61) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL822940 | 0.94 | HTR1A (0.61) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL823058 | 0.94 | HTR1A (0.61) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL1950024 | 0.94 | HTR1A (0.61) | HTR1AHTR7DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL29064497 | 0.92 | HTR1A (0.59) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL9945844 | 0.85 | HTR1A (0.55) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL11636988 | 0.84 | SIGMAR1 (0.56) | HTR1AHTR7DRD2DRD4DRD3 | |
| SCHEMBL2248107 | 0.80 | DRD3 (0.54) | HTR1AHTR7DRD3 | |
| SCHEMBL31808827 | 0.80 | DRD3 (0.54) | HTR1AHTR7DRD3 | |
| Bromide SCHEMBL29349994 | 0.78 | HTR1A (0.56) | HTR1AHTR7DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117730073-A | Serotonin 5-HT2A, 5-HT2B and 5-HT2C receptor inverse agonists | 东北大学 | 2024-03-19 | — | — | CN | disclosed |