Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28611098 | 0.81 | TDP1 (0.53) | MAPTPOLBALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28920607 | 0.81 | HSPB1 (0.47) | MAPTALDH1A1HPGDNPC1CYP3A4 | |
| SCHEMBL11647517 | 0.80 | MAPT (0.55) | MAPTPOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8989557 | 0.78 | HPGD (0.51) | MAPTPOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL28931147 | 0.77 | HPGD (0.45) | MAPTALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL28410050 | 0.77 | ALDH1A1 (0.42) | MAPTALDH1A1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL15234445 | 0.77 | ERN1 (0.43) | MAPTALDH1A1SMN1; SMN2GAANPC1 | |
| SCHEMBL3721283 | 0.76 | MAPT (0.57) | MAPTPOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8926888 | 0.76 | MAPT (0.48) | MAPTPOLBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL30644791 | 0.75 | MAPT (0.50) | MAPTPOLBALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234728-A | Heterocyclic compounds for the treatment of cancer | 阿提奥斯医药有限公司 | 2024-06-21 | — | — | CN | disclosed |