Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CD69 | Q07108 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70162 | 0.89 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL3364649 | 0.89 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL31702246 | 0.89 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL70163 | 0.89 | TRPA1 (0.86) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL28611366 | 0.86 | TRPA1 (0.82) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL28018222 | 0.86 | TRPA1 (0.82) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL29163841 | 0.86 | TRPA1 (0.82) | TRPA1NPC1KMT2APOLBMEN1 | |
| SCHEMBL28018294 | 0.86 | TRPA1 (0.82) | TRPA1NPC1KMT2APOLBMEN1 | |
| Terephthalic Acid SCHEMBL29181739 | 0.86 | TSHR (0.71) | CA1CA2CA12CA9TP53 | |
| SCHEMBL17777821 | 0.86 | TRPA1 (0.62) | TRPA1NPC1KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589377-B | 4,4' -Azo-bis-benzoic acid ethylenediamine dye eutectic and preparation method thereof | 吉林医药学院 | 2024-11-29 | — | — | CN | claimed |
| CN-116589377-A | 4,4' -azo-bis-benzoic acid ethylenediamine dye eutectic and preparation method thereof | 吉林医药学院 | 2023-08-15 | — | — | CN | claimed |
| CN-116589377-B | 4,4' -Azo-bis-benzoic acid ethylenediamine dye eutectic and preparation method thereof | 吉林医药学院 | 2024-11-29 | — | — | CN | disclosed |
| CN-116589377-A | 4,4' -azo-bis-benzoic acid ethylenediamine dye eutectic and preparation method thereof | 吉林医药学院 | 2023-08-15 | — | — | CN | disclosed |
| CN-116589377-A | 4,4' -azo-bis-benzoic acid ethylenediamine dye eutectic and preparation method thereof | 吉林医药学院 | 2023-08-15 | — | — | CN | disclosed |
| CN-116589377-A | 4,4' -azo-bis-benzoic acid ethylenediamine dye eutectic and preparation method thereof | 吉林医药学院 | 2023-08-15 | — | — | CN | disclosed |