Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236320 | 0.89 | CYP3A4 (0.55) | TNFRSF1ALMNASMN1; SMN2HPGDABCG2 | |
| SCHEMBL29236435 | 0.82 | MAOB (0.63) | TNFRSF1ASMN1; SMN2ABCG2MAPTMAOB | |
| SCHEMBL3704563 | 0.77 | KDM4E (0.54) | LMNASMN1; SMN2HPGDATMMAPT | |
| SCHEMBL2818992 | 0.77 | KDM4E (0.54) | LMNASMN1; SMN2HPGDATMMAPT | |
| SCHEMBL6586583 | 0.76 | TNFRSF1A (0.82) | TNFRSF1ALMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL11797296 | 0.76 | TNFRSF1A (0.82) | TNFRSF1ALMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL6593521 | 0.76 | TNFRSF1A (0.82) | TNFRSF1ALMNASMN1; SMN2MAPTMAOA | |
| SCHEMBL12948677 | 0.73 | CYP3A4 (0.62) | TNFRSF1ALMNASMN1; SMN2HPGDMAPT | |
| SCHEMBL973107 | 0.73 | CYP3A4 (0.62) | TNFRSF1ALMNASMN1; SMN2HPGDMAPT | |
| 4-Fluoro Chalcone SCHEMBL657888 | 0.73 | TNFRSF1A (0.82) | TNFRSF1ALMNAHPGDMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986188-A | Preparation method of 9-alkenyl substituted acridine derivative | 郑州原理生物科技有限公司 | 2024-05-07 | — | — | CN | disclosed |