Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.82 |
| ▸ | CYP1B1 | Q16678 | 12/20 | 0.75 |
| ▸ | MAOB | P27338 | 6/20 | 0.75 |
| ▸ | MAPT | P10636 | 4/20 | 0.75 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | BCHE | P06276 | 1/20 | 0.75 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | RECQL | P46063 | 1/20 | 0.75 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.75 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | HSPD1 | P10809 | 3/20 | 0.71 |
| ▸ | HSPE1 | P61604 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | MAOA | P21397 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.71 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.71 |
| ▸ | F3 | P13726 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797296 | 1.00 | TNFRSF1A (0.82) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 | |
| SCHEMBL6593521 | 1.00 | TNFRSF1A (0.82) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 | |
| 4-Fluoro Chalcone SCHEMBL657887 | 0.93 | TNFRSF1A (0.82) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 | |
| 4-Fluoro Chalcone SCHEMBL657888 | 0.93 | TNFRSF1A (0.82) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 | |
| 4-Fluoro Chalcone SCHEMBL10363601 | 0.93 | TNFRSF1A (0.82) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 | |
| SCHEMBL7196521 | 0.90 | TNFRSF1A (1.00) | TNFRSF1ACYP1B1MAOBMAPTMAOA | |
| SCHEMBL5593308 | 0.90 | TNFRSF1A (1.00) | TNFRSF1ACYP1B1MAOBMAPTMAOA | |
| SCHEMBL25221701 | 0.87 | TNFRSF1A (0.86) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 | |
| SCHEMBL1393290 | 0.87 | TNFRSF1A (0.86) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 | |
| SCHEMBL1393287 | 0.87 | TNFRSF1A (0.86) | TNFRSF1ACYP1B1MAOBMAPTPLIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620901-B | Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof | 杭州师范大学 | 2023-02-10 | — | — | CN | claimed |
| EP-4567018-A1 | METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUND | DAIKIN INDUSTRIES, LTD. (JP) | 2025-06-11 | — | — | EP | disclosed |
| CN-119799009-A | High-heat-conductivity high-temperature-aging-resistant heat-conducting gel and preparation method thereof | 万华化学集团股份有限公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-117843626-A | Ketone Kangxian-based triazole analogue, and preparation method and application thereof | 宿迁晨阳医药科技有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117384199-A | Preparation of novel organic aluminum hydrogen compound and preparation method of unsaturated alcohol compound catalyzed by novel organic aluminum hydrogen compound | 北京理工大学 | 2024-01-12 | — | — | CN | disclosed |
| CN-115368268-B | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-116284114-A | Method for synthesizing chiral 1, 3-phosphine alcohol | 陕西师范大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115894345-A | Method for photocatalytic synthesis of chiral aza-arene functionalized cyclobutane compound | 河南工业大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-113620901-B | Crown ether derived chiral 1,1 '-bi-2, 2' -naphthol, preparation method and application thereof | 杭州师范大学 | 2023-02-10 | — | — | CN | disclosed |
| CN-115368268-A | Method for efficiently preparing azo compound and application thereof | 大连理工大学 | 2022-11-22 | — | — | CN | disclosed |
| WO-2001051472-A1 | NEW IMIDAZOLE DERIVATIVES | ORION CORPORATION (FI) | 2001-07-19 | — | — | WO | disclosed |
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | disclosed |
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |
| US-5360819-A | Nonradioactive labels which provide a ketone signal, vapor phase analysis | NORTHEASTERN UNIVERSITY (US) | 1994-11-01 | — | — | US | disclosed |
| EP-0540604-A1 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Aventis Pharma S.A. (FR) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |
| US-5072023-A | Reacting lactone with ester anion to form cyclohexenone ester; oxidizing or dehydrogenating the intermediate | E. R. SQUIBB & SONS, INC. (US) | 1991-12-10 | — | — | US | disclosed |
| EP-0442495-A1 | Process for preparing highly substituted phenyls | E.R. SQUIBB & SONS, INC. (US) | 1991-08-21 | — | — | EP | disclosed |