SCHEMBL2818992

SCHEMBL2818992

O=C(O)C=Cc1c2ccccc2nc2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.54
LMNA P02545 1/20 0.54
RAB9A P51151 2/20 0.50
HDAC3 O15379 1/20 0.50
TNKS O95271 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HCAR2 Q8TDS4 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
TNKS2 Q9H2K2 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
ERN1 O75460 1/20 0.45
HSD17B10 Q99714 2/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3704563 1.00 KDM4E (0.54) KDM4ELMNARAB9AHDAC3TNKS
SCHEMBL6852611 0.86 HCAR2 (0.60) KDM4ELMNAHDAC3TNKSHDAC4
SCHEMBL6852607 0.86 HCAR2 (0.60) KDM4ELMNAHDAC3TNKSHDAC4
SCHEMBL29236320 0.84 CYP3A4 (0.55) KDM4ELMNARAB9AHDAC3HDAC4
SCHEMBL4660259 0.83 KDM1A (0.43) KDM4ELMNARAB9ACA1CA2
SCHEMBL9682211 0.81 KMT2A (0.54) KDM4ERAB9AERN1CA1CA2
SCHEMBL9682795 0.81 KMT2A (0.54) KDM4ERAB9AERN1CA1CA2
SCHEMBL8854345 0.81 CYP2D6 (0.58) KDM4ELMNARAB9AHDAC3TNKS
Phenazine SCHEMBL28375190 0.79 ALDH1A1 (0.56) KDM4ELMNARAB9AHDAC3TNKS
SCHEMBL29236286 0.77 ALOX5 (0.55) KDM4ELMNAKMT2AALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0360443-A1 Acridine compound and photopolymerizable composition using the same Hitachi Chemical Co., Ltd. (JP) 1990-03-28 EP claimed
JP-2069463-A None JP disclosed
US-20180141315-A1 INTERLAYER FILLING MATERIAL FOR TOUCH PANELS, AND TOUCH PANEL LAMINATE SEKISUI CHEMICAL CO., LTD. (JP) 2018-05-24 US disclosed
EP-3296846-A1 INTERLAYER FILLING MATERIAL FOR TOUCH PANELS, AND TOUCH PANEL LAMINATE Sekisui Chemical Co., Ltd. (JP) 2018-03-21 EP disclosed
US-9323108-B2 Liquid curable resin composition, method for manufacturing image display device using same, and image display device HITACHI CHEMICAL COMPANY, LTD. (JP) 2016-04-26 US disclosed
US-9012028-B2 Optical resin composition, optical resin material using the same, optical HITACHI CHEMICAL COMPANY, LTD. (JP) 2015-04-21 US disclosed
US-20140368759-A1 LIQUID CURABLE RESIN COMPOSITION, METHOD FOR MANUFACTURING IMAGE DISPLAY DEVICE USING SAME, AND IMAGE DISPLAY DEVICE RESONAC CORPORATION (JP) 2014-12-18 US disclosed
EP-2796504-A2 Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device Hitachi Chemical Co., Ltd. (JP) 2014-10-29 EP disclosed
US-8859683-B2 Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-10-14 US disclosed
US-8653200-B2 Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device HITACHI CHEMICAL CO., LTD. (JP) 2014-02-18 US disclosed
US-20100247940-A1 Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device HITACHI CHEMICAL CO., LTD. (JP) 2010-09-30 US disclosed
CN-101675083-A Resin composition for optical use and resin material for optical use using the same HITACHI CHEMICAL CO LTD 2010-03-17 CN disclosed
EP-2053087-A1 RESIN COMPOSITION FOR OPTICAL USE, RESIN MATERIAL FOR OPTICAL USE USING THE SAME, OPTICAL FILTER FOR IMAGE DISPLAY DEVICE, AND IMAGE DISPLAY DEVICE Hitachi Chemical Co., Ltd. (JP) 2009-04-29 EP disclosed
EP-0398713-B1 Photosensitive resin composition and laminate using the same HITACHI CHEMICAL CO LTD (JP) 1994-07-20 EP disclosed
US-5089377-A Acridin-9-yl acrylates ASAHI DENKA KOGYO K.K. (JP) 1992-02-18 US disclosed
US-4985564-A Acridine compound and photopolymerizable composition using the same HITACHI CHEMICAL CO., LTD. (JP) 1991-01-15 US disclosed
US-4980266-A Excellent stability and resistance to plating HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-12-25 US disclosed
EP-0398713-A2 Photosensitive resin composition and laminate using the same Hitachi Chemical Co., Ltd. (JP) 1990-11-22 EP disclosed
EP-0360443-A1 Acridine compound and photopolymerizable composition using the same Hitachi Chemical Co., Ltd. (JP) 1990-03-28 EP disclosed
JP-H0269463-A ACRIDINE COMPOUND ADEKA ARGUS CHEM CO LTD 1990-03-08 JP disclosed