Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 6/20 | 0.34 |
| ▸ | MTOR | P42345 | 4/20 | 0.34 |
| ▸ | IDH2 | P48735 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236532 | 0.76 | IDH2 (0.35) | PIK3CAIDH2PIK3CDPIK3CBPIK3CG | |
| SCHEMBL23132942 | 0.75 | GAA (0.46) | PIK3CAMAPK14PIK3CDPIK3CBPIK3CG | |
| SCHEMBL29236507 | 0.75 | IDH2 (0.33) | PIK3CAIDH2PIK3CDPIK3CBPIK3CG | |
| SCHEMBL31125217 | 0.73 | — | — | |
| SCHEMBL30461496 | 0.73 | AHR (0.34) | PIK3CAMAPK14PIK3CDPIK3CBPIK3CG | |
| SCHEMBL25223348 | 0.73 | AHR (0.34) | PIK3CAMAPK14PIK3CDPIK3CBPIK3CG | |
| SCHEMBL29552184 | 0.72 | PDE3B (0.36) | PIK3CAMTORIDH2MAPK14CSNK1E | |
| SCHEMBL14720958 | 0.72 | BACE1 (0.42) | MAPK14CSNK1ECSNK1DBACE1KCNH2 | |
| SCHEMBL6395910 | 0.72 | PDE3B (0.36) | PIK3CAMTORIDH2MAPK14CSNK1E | |
| SCHEMBL9882583 | 0.71 | MAPK14 (0.34) | PIK3CAMAPK14PIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184639-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-06-14 | — | — | CN | disclosed |