Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 4/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.31 |
| ▸ | FABP7 | O15540 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | FABP3 | P05413 | 1/20 | 0.30 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236525 | 0.76 | PIK3CA (0.34) | IDH2SUV39H2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL23132942 | 0.70 | GAA (0.46) | GCKMAPTSUV39H2PIK3CDPIK3CA | |
| SCHEMBL29236507 | 0.70 | IDH2 (0.33) | IDH2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL27621218 | 0.68 | GAA (0.42) | TSHR | |
| SCHEMBL25295762 | 0.67 | CYP1A2 (0.36) | CYP11B2 | |
| SCHEMBL26090166 | 0.67 | CD44 (0.35) | MAPTTSHR | |
| SCHEMBL29236517 | 0.67 | IDO1 (0.33) | MAPT | |
| SCHEMBL29177226 | 0.64 | SMN1; SMN2 (0.35) | MAPTCYP11B2 | |
| SCHEMBL28105760 | 0.64 | L3MBTL1 (0.34) | — | |
| SCHEMBL9882583 | 0.64 | MAPK14 (0.34) | PIM1PIM2SUV39H2PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184639-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-06-14 | — | — | CN | disclosed |