Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29236525 | 0.75 | PIK3CA (0.34) | IDH2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7931545 | 0.70 | TDP1 (0.45) | — | |
| SCHEMBL29236532 | 0.70 | IDH2 (0.35) | IDH2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL10347965 | 0.69 | TDP1 (0.39) | — | |
| SCHEMBL9882583 | 0.65 | MAPK14 (0.34) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9036874 | 0.65 | CA12 (0.47) | — | |
| SCHEMBL9836795 | 0.65 | CYP3A4 (0.42) | — | |
| SCHEMBL28565939 | 0.63 | TDP1 (0.41) | — | |
| SCHEMBL7894600 | 0.62 | TDP1 (0.38) | — | |
| SCHEMBL7929412 | 0.62 | TDP1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184639-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-06-14 | — | — | CN | disclosed |