Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217386 | 1.00 | SCN9A (0.36) | SCN9ATHRATHRBKDRTRPA1 | |
| SCHEMBL30967808 | 0.88 | TRPA1 (0.34) | SCN9ATHRATHRBKDRTRPA1 | |
| SCHEMBL29237596 | 0.88 | TRPA1 (0.34) | SCN9ATHRATHRBKDRTRPA1 | |
| SCHEMBL27275536 | 0.87 | NR4A2 (0.39) | THRATHRBTRPA1SCN8ASCN10A | |
| SCHEMBL31108604 | 0.87 | NR4A2 (0.39) | THRATHRBTRPA1SCN8ASCN10A | |
| SCHEMBL30217071 | 0.83 | TRPA1 (0.34) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29237459 | 0.83 | TRPA1 (0.34) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27275532 | 0.77 | RHEB (0.42) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31108517 | 0.77 | RHEB (0.42) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31108631 | 0.76 | NR4A2 (0.39) | SCN9ATHRATHRBTRPA1SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |