Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | RHEB | Q15382 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237596 | 1.00 | TRPA1 (0.34) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29237459 | 0.88 | TRPA1 (0.34) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL30217071 | 0.88 | TRPA1 (0.34) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL29237201 | 0.88 | SCN9A (0.36) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL30217386 | 0.88 | SCN9A (0.36) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27275536 | 0.87 | NR4A2 (0.39) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31108604 | 0.87 | NR4A2 (0.39) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL30750345 | 0.83 | BTK (0.37) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27277710 | 0.83 | BTK (0.37) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL31108517 | 0.79 | RHEB (0.42) | TRPA1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |