SCHEMBL2923743

SCHEMBL2923743

CCCCCCCCC[SiH](C)Cl

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.43
DNM1 Q05193 7/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A1 O15245 1/20 0.36
EPHX1 P07099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7750716 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL7649051 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6673591 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL4247523 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL1820763 1.00
SCHEMBL24062094 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6576515 0.97
SCHEMBL1042169 0.88
SCHEMBL7075981 0.87
SCHEMBL31135073 0.81 LMNA (0.46) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006058995-A2 MULTIFUNCTIONALIZED MESOSTRUCTURED POROUS OXIDE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) 2006-06-08 WO claimed
EP-0315633-B1 BONDED CHROMATOGRAPHIC STATIONARY PHASE 3i RESEARCH EXPLOITATION LIMITED (GB) 1991-10-23 EP claimed
EP-2212379-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT Société de Technologie MICHELIN (FR) 2010-08-04 EP disclosed
WO-2009062733-A2 RUBBER COMPOSITION FOR A TYRE COMPRISING A HYDROXYSILANE COVERING AGENT SOCIETE DE TECHNOLOGIE MICHELIN (FR) 2009-05-22 WO disclosed
WO-2006058995-A2 MULTIFUNCTIONALIZED MESOSTRUCTURED POROUS OXIDE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) 2006-06-08 WO disclosed