SCHEMBL6673591

SCHEMBL6673591

CCCCCCCC[SiH](C)Cl

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.47
THRB P10828 1/20 0.47
ALDH1A1 P00352 3/20 0.43
DNM1 Q05193 7/20 0.36
LMNA P02545 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HSD17B10 Q99714 1/20 0.36
SLC22A1 O15245 1/20 0.36
EPHX1 P07099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7750716 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL7649051 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL4247523 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL2923743 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL1820763 1.00
SCHEMBL24062094 1.00 TSHR (0.47) TSHRTHRBALDH1A1DNM1LMNA
SCHEMBL6576515 0.97
SCHEMBL1042169 0.88
SCHEMBL7075981 0.87
SCHEMBL31135073 0.81 LMNA (0.46) TSHRTHRBALDH1A1DNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016144811-A1 COATED MAGNETIC PARTICLE AND METHODS OF MAKING AND USING THE SAME SDCmaterials, Inc. (US) 2016-09-15 WO claimed
CN-109313178-A Counteracting osmotic imbalances in nanopore sequencing cells 豪夫迈·罗氏有限公司 2019-02-05 CN disclosed
CN-101286021-B Toner, two-component developer and image forming apparatus using the toner RICOH CO LTD 2011-07-27 CN disclosed
CN-1837221-B Production processes for triorganomonochlorosilanes HOKKO CHEM IND CO 2011-06-08 CN disclosed
CN-101286021-A Toner, two-component developer and image forming apparatus using the toner RICOH KK (JP) 2008-10-15 CN disclosed
CN-1296374-C Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2007-01-24 CN disclosed
CN-1837221-A Production processes for triorganomonochlorosilanes HOKKO CHEM IND CO (JP) 2006-09-27 CN disclosed
CN-1612886-A Method for producing triorgano-monoalkoxysilanes and method for producing triorgano-monochlorosilanes HOKKO CHEM IND CO (JP) 2005-05-04 CN disclosed
EP-0969007-B1 Method of making an aromatic chlorosilane compound by a hydrosilation reaction DOW CORNING ASIA LTD (JP) 2004-09-22 EP disclosed
US-6790575-B2 FOR IMAGE FORMING UTILIZING AN ELECTROPHOTOGRAPHY OR ELECTROSTATIC PRINTING USED IN COPIERS, PRINTERS, AND FACSIMILES RICOH COMPANY, LTD. (JP) 2004-09-14 US disclosed
US-20030073021-A1 Two-component developer, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2003-04-17 US disclosed
US-6054602-A Method of making an aromatic chlorosilane compound by a hydrosilation reaction DOW CORNING ASIA, LTD. (JP) 2000-04-25 US disclosed
EP-0969007-A2 Method of making an aromatic chlorosilane compound by a hydrosilation reaction Dow Corning Asia, Ltd. (JP) 2000-01-05 EP disclosed
US-5869724-A REAGENTS FOR MODIFYING THE SURFACE OF LIQUID CHROMATOGRAPHY SUPPORTS HEWLETT-PACKARD COMPANY (US) 1999-02-09 US disclosed
EP-0635533-B1 Polyimide-based liquid crystal aligning agent SAGAMI CHEM RES (JP) 1998-06-10 EP disclosed
EP-0452725-B1 Fluorine containing diaminobenzene derivatives and its use SAGAMI CHEM RES (JP) 1995-11-08 EP disclosed
EP-0635533-A1 Polyimide-based liquid crystal aligning agent SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-01-25 EP disclosed
US-5153304-A Polyimides; liquid crystal tilting agent; water-repelling SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-10-06 US disclosed
US-5144078-A Polyimide intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-09-01 US disclosed
EP-0452725-A2 Fluorine containing diaminobenzene derivatives and its use SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-23 EP disclosed