Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15322746 | 0.85 | BACE1 (0.58) | BACE1KMT2AOPRM1TTRDPP4 | |
| SCHEMBL15322749 | 0.85 | BACE1 (0.58) | BACE1KMT2AOPRM1TTRDPP4 | |
| SCHEMBL30217190 | 0.83 | OPRM1 (0.58) | BACE1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL29237501 | 0.80 | OPRM1 (0.41) | KMT2AOPRM1OPRD1OPRK1SLC22A1 | |
| SCHEMBL30217340 | 0.77 | BACE1 (0.52) | BACE1KMT2AOPRM1TTRDPP4 | |
| SCHEMBL30967833 | 0.77 | BACE1 (0.52) | BACE1KMT2AOPRM1TTRDPP4 | |
| SCHEMBL29237214 | 0.77 | BACE1 (0.52) | BACE1KMT2AOPRM1TTRDPP4 | |
| SCHEMBL29237211 | 0.77 | BACE1 (0.52) | BACE1KMT2AOPRM1TTRDPP4 | |
| SCHEMBL15322548 | 0.77 | BACE1 (0.49) | BACE1KMT2AOPRM1OPRD1OPRK1 | |
| SCHEMBL29237660 | 0.73 | KMT2A (0.39) | KMT2AOPRM1OPRD1OPRK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |