Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.58 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15322749 | 0.85 | BACE1 (0.58) | OPRM1BACE1KMT2ATTRDPP4 | |
| SCHEMBL15322746 | 0.85 | BACE1 (0.58) | OPRM1BACE1KMT2ATTRDPP4 | |
| SCHEMBL29237570 | 0.83 | BACE1 (0.48) | OPRM1OPRD1OPRK1BACE1KMT2A | |
| SCHEMBL30217226 | 0.80 | OPRM1 (0.59) | OPRM1OPRD1OPRK1KMT2AKDM4E | |
| SCHEMBL30217340 | 0.77 | BACE1 (0.52) | OPRM1BACE1KMT2ATTRDPP4 | |
| SCHEMBL29237214 | 0.77 | BACE1 (0.52) | OPRM1BACE1KMT2ATTRDPP4 | |
| SCHEMBL29237211 | 0.77 | BACE1 (0.52) | OPRM1BACE1KMT2ATTRDPP4 | |
| SCHEMBL30967833 | 0.77 | BACE1 (0.52) | OPRM1BACE1KMT2ATTRDPP4 | |
| SCHEMBL15322548 | 0.77 | BACE1 (0.49) | OPRM1OPRD1OPRK1BACE1KMT2A | |
| SCHEMBL4872645 | 0.76 | OPRD1 (0.56) | OPRM1OPRD1OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396179-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2024-07-10 | — | — | EP | disclosed |
| WO-2023034992-A1 | INDOLE COMPOUNDS AND METHODS OF USE | GENZYME CORPORATION (US) | 2023-03-09 | — | — | WO | disclosed |