Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29225600 | 0.98 | LPO (0.39) | LPOPTP4A3HTTKMT2AALDH1A1 | |
| SCHEMBL18272521 | 0.98 | LPO (0.39) | LPOPTP4A3HTTKMT2AALDH1A1 | |
| Iodide SCHEMBL29238256 | 0.96 | LPO (0.38) | LPOPTP4A3HTTKMT2AALDH1A1 | |
| SCHEMBL15871029 | 0.81 | LPO (0.48) | LPOPTP4A3HTTKMT2AALDH1A1 | |
| SCHEMBL1219965 | 0.79 | — | — | |
| SCHEMBL16869607 | 0.78 | LPO (0.35) | LPOPTP4A3HTTFDPS | |
| Bromide SCHEMBL28462643 | 0.78 | LPO (0.41) | LPOPTP4A3HTTKMT2AALDH1A1 | |
| SCHEMBL29006302 | 0.78 | MGLL (0.41) | KMT2AALDH1A1POLBTLR8 | |
| SCHEMBL29006290 | 0.78 | MGLL (0.41) | KMT2AALDH1A1POLBTLR8 | |
| SCHEMBL23367993 | 0.77 | KMT2A (0.35) | KMT2AALDH1A1POLBTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117899933-A | Supported single-atom Rh or Ir-based catalyst and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2024-04-19 | — | — | CN | claimed |
| CN-117899933-A | Supported single-atom Rh or Ir-based catalyst and preparation method and application thereof | 中国科学院大连化学物理研究所 | 2024-04-19 | — | — | CN | disclosed |