Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.35 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425694 | 0.85 | ESR1 (0.52) | KIF11ABHD6KDM4EESR1ESR2 | |
| SCHEMBL29104009 | 0.84 | KIF11 (0.44) | KIF11CAMK2AABHD6DPP8DPP9 | |
| SCHEMBL29238589 | 0.84 | ESR2 (0.49) | KIF11ABHD6HSP90AA1ESR1ESR2 | |
| SCHEMBL20425577 | 0.83 | ESR1 (0.51) | KIF11ABHD6ESR1ESR2 | |
| SCHEMBL12279527 | 0.81 | USP30 (0.47) | KIF11ABHD6NAMPTKDM4EESR2 | |
| SCHEMBL30970501 | 0.81 | USP30 (0.47) | KIF11ABHD6NAMPTKDM4EESR2 | |
| SCHEMBL31597608 | 0.81 | USP30 (0.47) | KIF11ABHD6NAMPTKDM4EESR2 | |
| SCHEMBL38664529 | 0.79 | KIF11 (0.42) | KIF11ABHD6DPP8DPP9DPP7 | |
| SCHEMBL13886242 | 0.78 | ABHD6 (0.59) | ABHD6KMT2A | |
| SCHEMBL19643493 | 0.76 | AKR1B1 (0.43) | KIF11ABHD6DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117956996-A | Compounds and methods for YAP/TEAD modulation and indications therefor | OPNA 生物公司 | 2024-04-30 | — | — | CN | disclosed |