Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167773 | 0.97 | MEN1 (0.50) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL1404483 | 0.92 | KMT2A (0.46) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL18429374 | 0.91 | MEN1 (0.45) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL11989400 | 0.90 | TDP1 (0.58) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL29130881 | 0.89 | MAOA (0.48) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL22433669 | 0.89 | TDP1 (0.47) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL13143837 | 0.89 | CA14 (0.43) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL12482641 | 0.87 | TDP1 (0.56) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL7154749 | 0.87 | MEN1 (0.42) | MEN1GAAKMT2ATDP1EPHX1 | |
| SCHEMBL18362433 | 0.86 | TDP1 (0.49) | MEN1GAAKMT2ATDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695259-A1 | TRICYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024213610-A1 | TRICYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-17 | — | — | WO | disclosed |
| CN-117750982-A | Coupling reagent and conjugate thereof | 剑桥实业有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2023006782-A1 | CONJUGATING REAGENTS AND CONJUGATES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2023-02-02 | — | — | WO | disclosed |