Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3167773 | 0.92 | MEN1 (0.50) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL29239019 | 0.92 | MEN1 (0.50) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL270450 | 0.89 | TDP1 (0.51) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL18429374 | 0.86 | MEN1 (0.45) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL29130881 | 0.85 | MAOA (0.48) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL22433669 | 0.84 | TDP1 (0.47) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL18902123 | 0.84 | TDP1 (0.42) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL12482641 | 0.83 | TDP1 (0.56) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL11989400 | 0.83 | TDP1 (0.58) | KMT2AMEN1GAATDP1EPHX1 | |
| SCHEMBL15889841 | 0.83 | TDP1 (0.54) | KMT2AMEN1GAATDP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10036066-B2 | In situ hybridization detection method | DAKO DENMARK A/S (DK) | 2018-07-31 | — | — | US | disclosed |
| US-9598720-B2 | Monomeric and polymeric linkers useful for conjugating biological molecules and other substances | DAKO DENMARK A/S (DK) | 2017-03-21 | — | — | US | disclosed |
| US-20160273035-A1 | IN SITU HYBRIDIZATION DETECTION METHOD | DAKO DENMARK A/S (DK) | 2016-09-22 | — | — | US | disclosed |
| EP-1919930-B1 | NEW NUCLEIC ACID BASE PAIRS | DAKO DENMARK AS (DK) | 2016-09-14 | — | — | EP | disclosed |
| WO-2016043661-A1 | MODIFIED PEPTIDE NUCLEIC ACIDS AND THEIR USE | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-03-24 | — | — | WO | disclosed |
| US-9017992-B2 | In situ hybridization detection method | DAKO DENMARK A/S (DK) | 2015-04-28 | — | — | US | disclosed |
| EP-1910575-B1 | IMMUNOHISTOCHEMISTRY DETECTION METHOD | DAKO DENMARK AS (DK) | 2014-12-10 | — | — | EP | disclosed |
| US-8741566-B2 | Immunohistochemistry and in situ hybridization detection method | DAKO DENMARK A/S (DK) | 2014-06-03 | — | — | US | disclosed |
| US-20140080145-A1 | Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances | DAKO DENMARK A/S (DK) | 2014-03-20 | — | — | US | disclosed |
| US-8546309-B2 | Monomeric and polymeric linkers useful for conjugating biological molecules and other substances | DAKO DENMARK A/S (DK) | 2013-10-01 | — | — | US | disclosed |
| US-20110177500-A1 | IMMUNOHISTOCHEMISTRY DETECTION METHOD | DAKO DENMARK AS (DK) | 2011-07-21 | — | — | US | disclosed |
| EP-1907592-B1 | MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES | DAKO DENMARK AS (DK) | 2011-03-09 | — | — | EP | disclosed |
| US-20100284959-A1 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENE ARREST LTD. (IL) | 2010-11-11 | — | — | US | disclosed |
| US-20100221705-A1 | IN SITU HYBRIDIZATION DETECTION METHOD | DAKO DENMARK APS (DK) | 2010-09-02 | — | — | US | disclosed |
| US-20100120054-A1 | MONOMERIC AND POLYMERIC LINKERS USEFUL FOR CONJUGATING BIOLOGICAL MOLECULES AND OTHER SUBSTANCES | DAKO DENMARK APS (DK) | 2010-05-13 | — | — | US | disclosed |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | DAKO DENMARK A/S (DK) | 2010-04-29 | — | — | US | disclosed |
| US-20100105145-A1 | METHOD OF SIMULTANEOUSLY VISUALIZING MULTIPLE BIOLOGICAL TARGETS | DAKO DENMARK A/S (DK) | 2010-04-29 | — | — | US | disclosed |
| US-7282575-B2 | Functional peptide nucleic acid monomer and process for producing the same | CREDIA JAPAN CO., LTD. (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20030207804-A1 | Modified peptide nucleic acids | ISIS PHARMACEUTICALS, INC. | 2003-11-06 | — | — | US | disclosed |
| WO-2002097134-A2 | MODIFIED PEPTIDE NUCLEIC ACID | ISIS PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284959-A1 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | POLRMT, POLM, SNRPE | KMT2A 2479/4885MEN1 4592/4885GAA 913/4885 |
| US-20140080145-A1 | Monomeric and Polymeric Linkers Useful For Conjugating Biological Molecules and Other Substances | PCNA, DCLRE1A, TK1 | KMT2A 2158/4885MEN1 784/4885GAA 1024/4885 |
| US-20030207804-A1 | Modified peptide nucleic acids | NGLY1, PARN, NPPA | KMT2A 1937/4885MEN1 513/4885GAA 1697/4885 |
| US-20100105030-A1 | NUCLEIC ACID BASE PAIRS | NSUN3, NCL, NSUN2 | KMT2A 1811/4885MEN1 1256/4885GAA 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.