Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 4/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | RGS4 | P49798 | 6/20 | 0.54 |
| ▸ | RGS8 | P57771 | 4/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239097 | 0.86 | GSK3B (0.71) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL29239059 | 0.82 | GSK3B (0.76) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL30893118 | 0.79 | GSK3B (0.59) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL6426900 | 0.79 | GSK3B (0.59) | GSK3BHDAC6RGS4RGS8GSK3A | |
| Tideglusib SCHEMBL676929 | 0.78 | GSK3B (1.00) | GSK3BHDAC6RGS4RGS8GSK3A | |
| Tideglusib SCHEMBL29357303 | 0.78 | GSK3B (1.00) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL29239076 | 0.77 | GSK3B (0.81) | GSK3BHDAC6RGS4RGS8TDP1 | |
| SCHEMBL29239083 | 0.75 | GSK3B (0.83) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL29239070 | 0.74 | GSK3B (0.69) | GSK3BHDAC6RGS4RGS8GSK3A | |
| SCHEMBL29239080 | 0.74 | GSK3B (0.81) | GSK3BHDAC6RGS4RGS8GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113827592-B | Application of thiadiazolidinedione compound in treating pathogenic infection | 中国科学院上海药物研究所 | 2024-06-18 | — | — | CN | disclosed |