Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3819754 | 1.00 | HTR2C (0.44) | HTR2CALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL23093716 | 1.00 | HTR2C (0.44) | HTR2CALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL22278696 | 0.83 | ALOX15 (0.45) | ALOX15HSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL23102395 | 0.83 | ALOX15 (0.45) | ALOX15HSD17B10ALDH1A1KDM4EMAPT | |
| SCHEMBL29088933 | 0.82 | KMT2A (0.63) | HTR2CALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL5129484 | 0.82 | SMN1; SMN2 (0.42) | HTR2CALOX15HSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL27242739 | 0.82 | ALDH1A1 (0.58) | HTR2CALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL3821224 | 0.82 | ALDH1A1 (0.58) | HTR2CALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL29114224 | 0.81 | HSD17B10 (0.69) | HTR2CALOX15HSD17B10ALDH1A1KDM4E | |
| SCHEMBL29170650 | 0.79 | KDM4E (0.46) | ALOX15HSD17B10ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005655-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-05-10 | — | — | CN | disclosed |