Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | AXL | P30530 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239264 | 1.00 | PRKCQ (0.43) | PRKCQHTR2CAXLBRD4P2RX7 | |
| SCHEMBL11456017 | 0.74 | HTR2C (0.49) | HTR2C | |
| SCHEMBL26915074 | 0.73 | HTR2C (0.47) | HTR2CHTR6 | |
| SCHEMBL30729654 | 0.73 | HTR2C (0.47) | HTR2CHTR6 | |
| SCHEMBL26915066 | 0.73 | HTR2C (0.47) | HTR2CHTR6 | |
| Hydrochloric Acid SCHEMBL6421986 | 0.72 | HTR2C (0.49) | HTR2C | |
| SCHEMBL30905836 | 0.71 | CDK2 (0.45) | PRKCQP2RX7HTR6ITKLMNA | |
| SCHEMBL29114220 | 0.70 | THRB (0.40) | HTR2CLMNAMAPTTHRB | |
| SCHEMBL29239267 | 0.67 | HTR2C (0.36) | HTR2C | |
| SCHEMBL24171954 | 0.65 | ITK (0.52) | BRD4HTR6ITKMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005655-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-05-10 | — | — | CN | disclosed |