Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 12/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.55 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239314 | 0.84 | TBXAS1 (0.57) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10223314 | 0.82 | CYP11B1 (0.69) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL10848277 | 0.80 | TBXAS1 (1.00) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL9193417 | 0.78 | TBXAS1 (0.54) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL14464035 | 0.78 | CYP11B1 (0.61) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL1024261 | 0.78 | CYP11B1 (0.84) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL4492287 | 0.77 | CYP19A1 (0.75) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL29239316 | 0.77 | TBXAS1 (0.72) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| Benzylimidazole SCHEMBL16236718 | 0.77 | TBXAS1 (0.80) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| Oxalic Acid SCHEMBL11534580 | 0.76 | CYP19A1 (0.81) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |