Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.75 |
| ▸ | TBXAS1 | P24557 | 10/20 | 0.74 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.65 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | QPCT | Q16769 | 1/20 | 0.64 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.64 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.62 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9853939 | 0.98 | CYP19A1 (0.73) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL4701021 | 0.87 | CYP19A1 (0.70) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL12639833 | 0.85 | CYP19A1 (0.68) | CYP19A1TBXAS1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL6302514 | 0.85 | CYP19A1 (0.68) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL10531228 | 0.85 | TBXAS1 (1.00) | CYP19A1TBXAS1 | |
| SCHEMBL11165819 | 0.85 | CYP19A1 (0.60) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| Hydrochloric Acid SCHEMBL10671782 | 0.84 | TBXAS1 (0.97) | CYP19A1TBXAS1 | |
| SCHEMBL1024261 | 0.84 | CYP11B1 (0.84) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL29239316 | 0.83 | TBXAS1 (0.72) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 | |
| SCHEMBL10999087 | 0.83 | TBXAS1 (0.72) | CYP19A1TBXAS1CYP11B1CYP11B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005563-A | N-benzyl imidazole derivative and preparation method and application thereof | 中国药科大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-110799500-B | Degradable imidazolium oligomers and polymers for antimicrobial applications | 新加坡科技研究局 | 2023-10-03 | — | — | CN | disclosed |
| EP-3621955-B1 | DEGRADABLE IMIDAZOLIUM OLIGOMER AND POLYMER FOR ANTIMICROBIAL APPLICATIONS | AGENCY SCIENCE TECH & RES (SG) | 2021-07-14 | — | — | EP | disclosed |
| EP-3621955-B1 | DEGRADABLE IMIDAZOLIUM OLIGOMER AND POLYMER FOR ANTIMICROBIAL APPLICATIONS | AGENCY SCIENCE TECH & RES (SG) | 2021-07-14 | — | — | EP | disclosed |
| US-10927100-B2 | Degradable imidazolium oligomer and polymer for antimicrobial applications | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-02-23 | — | — | US | disclosed |
| US-10927100-B2 | Degradable imidazolium oligomer and polymer for antimicrobial applications | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-02-23 | — | — | US | disclosed |
| EP-3060552-B1 | 1,3-DIPOLAR COMPOUND BEARING AN IMIDAZOLE FUNCTION AND PROCESS FOR MODIFYING AN UNSATURATED POLYMER BY GRAFTING | MICHELIN & CIE (FR) | 2020-12-02 | — | — | EP | disclosed |
| US-20200181122-A1 | Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-06-11 | — | — | US | disclosed |
| US-20200181122-A1 | Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-06-11 | — | — | US | disclosed |
| EP-3621955-A1 | DEGRADABLE IMIDAZOLIUM OLIGOMER AND POLYMER FOR ANTIMICROBIAL APPLICATIONS | Agency for Science, Technology and Research (SG) | 2020-03-18 | — | — | EP | disclosed |
| US-7514468-B2 | Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7300934-B2 | Benzamide nitriles | ROCHE PALO ALTO LLC (US) | 2007-11-27 | — | — | US | disclosed |
| US-20060194813-A1 | Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2006-08-31 | — | — | US | disclosed |
| EP-0986551-B1 | SULFONAMIDE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL (JP) | 2006-08-02 | — | — | EP | disclosed |
| EP-1633701-A1 | BENZAMIDE NITRILE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004106285-A1 | BENZAMIDE NITRILE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-12-09 | — | — | WO | disclosed |
| US-20040248949-A1 | Benzamide nitriles | ROCHE PALO ALTO LLC | 2004-12-09 | — | — | US | disclosed |
| US-6359134-B1 | ANTICOAGULANTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |
| WO-1999051590-A1 | SUBSTITUTED INDOLINONES AS KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194813-A1 | Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions | KDR, FLT1, EGFR | CYP19A1 296/4885TBXAS1 196/4885CYP11B1 97/4885 |
| US-10927100-B2 | Degradable imidazolium oligomer and polymer for antimicrobial applications | NOD2, CFTR, PUF60 | CYP19A1 4646/4885TBXAS1 2982/4885CYP11B1 3790/4885 |
| US-20040248949-A1 | Benzamide nitriles | CTSK, CTSS, CMA1 | CYP19A1 697/4885TBXAS1 1958/4885CYP11B1 1127/4885 |
| US-20200181122-A1 | Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications | NOD2, CFTR, PUF60 | CYP19A1 4646/4885TBXAS1 2982/4885CYP11B1 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.