Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28957815 | 0.83 | GPBAR1 (0.35) | — | |
| SCHEMBL29239391 | 0.81 | — | — | |
| SCHEMBL29239422 | 0.81 | SCN9A (0.30) | — | |
| SCHEMBL29150549 | 0.76 | PARP1 (0.31) | — | |
| SCHEMBL24993465 | 0.73 | GSK3B (0.34) | GRM2PSMB5HDAC3HDAC1HDAC2 | |
| SCHEMBL30865560 | 0.73 | GSK3B (0.34) | GRM2PSMB5HDAC3HDAC1HDAC2 | |
| SCHEMBL29239397 | 0.72 | CNR2 (0.33) | — | |
| SCHEMBL28876524 | 0.71 | CNR2 (0.34) | — | |
| SCHEMBL28876635 | 0.68 | ACVR1 (0.38) | — | |
| SCHEMBL28876734 | 0.67 | CNR2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |