Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28876734 | 0.89 | CNR2 (0.36) | CNR2CNR1 | |
| SCHEMBL29239387 | 0.85 | IKBKB (0.32) | — | |
| SCHEMBL31330381 | 0.85 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL29150549 | 0.76 | PARP1 (0.31) | — | |
| SCHEMBL23089475 | 0.76 | BACE1 (0.38) | HTR1ADRD2HTR2AHTR7HTR1D | |
| SCHEMBL28876524 | 0.74 | CNR2 (0.34) | CNR2 | |
| SCHEMBL24992664 | 0.74 | HTR1A (0.38) | CNR2CNR1HTR1ADRD2HTR2A | |
| SCHEMBL23089799 | 0.73 | ALOX5AP (0.36) | CNR2CNR1HTR1ADRD2HTR2A | |
| SCHEMBL29239409 | 0.72 | GRM2 (0.37) | — | |
| SCHEMBL23107837 | 0.71 | PDK2 (0.35) | CNR2CNR1HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |