Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28737030 | 0.81 | NNMT (0.33) | — | |
| SCHEMBL28876586 | 0.81 | NNMT (0.33) | — | |
| SCHEMBL29150564 | 0.80 | POLB (0.32) | NCEH1PKM | |
| SCHEMBL29202889 | 0.76 | CA2 (0.33) | — | |
| SCHEMBL28876635 | 0.76 | ACVR1 (0.38) | — | |
| SCHEMBL29239397 | 0.76 | CNR2 (0.33) | — | |
| SCHEMBL28931441 | 0.74 | NNMT (0.45) | — | |
| SCHEMBL23089277 | 0.73 | PARP1 (0.33) | PARP1PARP2PARP3 | |
| SCHEMBL28876608 | 0.72 | ALDH1A1 (0.35) | — | |
| SCHEMBL28876491 | 0.72 | NNMT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117915912-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117377673-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-117295737-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2023-12-26 | — | — | CN | disclosed |