Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3905171 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA7CHRNA4CHRNA5 | |
| SCHEMBL688825 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA7CHRNA4CHRNA5 | |
| SCHEMBL688697 | 0.73 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA7CHRNA4CHRNA5 | |
| SCHEMBL8686148 | 0.72 | BCHE (0.43) | SMN1; SMN2CHRNB2CHRNA7CHRNA4CHRNA5 | |
| SCHEMBL8680907 | 0.72 | EPHX1 (0.53) | SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL21801417 | 0.72 | SMN1; SMN2 (0.40) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL27529211 | 0.72 | EPHX1 (0.47) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8704065 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2CHRNB2CHRNA7CHRNA4CHRNA5 | |
| SCHEMBL7022735 | 0.72 | EPHX1 (0.43) | SMN1; SMN2CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL25177265 | 0.71 | SMN1; SMN2 (0.34) | SMN1; SMN2CHRNB2CHRNA7CHRNA4CHRNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073344-B | Preparation method and application of R- (1-tert-butyloxycarbonyl pyrrolidine-2-yl) acrylic acid | 苏州富士莱医药股份有限公司 | 2024-03-26 | — | — | CN | disclosed |