Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681185 | 0.85 | BCHE (0.49) | BCHEACHESMN1; SMN2CHRNB2CHRNA5 | |
| SCHEMBL8683160 | 0.81 | SMN1; SMN2 (0.35) | BCHEDPP4DPP8DPP9SMN1; SMN2 | |
| SCHEMBL688697 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL3905171 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL688825 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL8680907 | 0.73 | EPHX1 (0.53) | BCHEACHESMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL21801417 | 0.73 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8704065 | 0.73 | SMN1; SMN2 (0.37) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL29240010 | 0.72 | SMN1; SMN2 (0.35) | SMN1; SMN2CHRNB2CHRNA5CHRNA7CHRNA4 | |
| SCHEMBL14612609 | 0.71 | BCHE (0.46) | BCHEACHEDPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843983-A | Diphenylethane compounds containing a saturated heterocyclic group, their preparation, and their therapeutic use | SANKYO COMPANY, LIMITED (JP) | 1998-12-01 | — | — | US | disclosed |
| US-5556864-A | TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |