SCHEMBL29242564

SCHEMBL29242564

Cc1ccccc1S(=O)(=O)c1cc(C)c(N)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
ALDH1A1 P00352 5/20 0.50
HSD11B1 P28845 1/20 0.46
HTR6 P50406 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 2/20 0.42
HTT P42858 1/20 0.42
POLB P06746 2/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
LMNA P02545 1/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
GAA P10253 3/20 0.41
ABCC9 O60706 1/20 0.40
ABCC8 Q09428 1/20 0.40
KCNJ11 Q14654 1/20 0.40
KCNJ8 Q15842 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3947257 0.80 ALDH1A1 (0.50) KDM4EALDH1A1HTR6L3MBTL1MAPT
SCHEMBL6001994 0.79 HTR6 (0.59) KDM4EALDH1A1HSD11B1HTR6MEN1
SCHEMBL30513969 0.79 ALDH1A1 (0.56) KDM4EALDH1A1HSD11B1L3MBTL1MAPT
SCHEMBL29039876 0.79 ALDH1A1 (0.56) KDM4EALDH1A1HSD11B1L3MBTL1MAPT
SCHEMBL2068969 0.79 ALDH1A1 (0.53) KDM4EALDH1A1HSD11B1HTR6L3MBTL1
SCHEMBL31092469 0.78 HTR6 (0.57) KDM4EALDH1A1HSD11B1HTR6L3MBTL1
SCHEMBL1713160 0.78 HTR6 (0.57) KDM4EALDH1A1HSD11B1HTR6L3MBTL1
SCHEMBL475089 0.77 ALDH1A1 (0.55) KDM4EALDH1A1HSD11B1L3MBTL1MAPT
SCHEMBL29468592 0.77 ALDH1A1 (0.55) KDM4EALDH1A1HSD11B1L3MBTL1MAPT
(Phenylsulfonyl)Benzene SCHEMBL6332793 0.76 HTR6 (0.61) KDM4EALDH1A1HSD11B1HTR6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677515-B Diamine monomer, polyamide imide copolymer, polyamide imide film and preparation method 中国科学院宁波材料技术与工程研究所 2024-03-29 CN disclosed