Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.53 |
| ▸ | PI4KA | P42356 | 6/20 | 0.49 |
| ▸ | PI4K2B | Q8TCG2 | 6/20 | 0.49 |
| ▸ | PI4K2A | Q9BTU6 | 6/20 | 0.49 |
| ▸ | PI4KB | Q9UBF8 | 6/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580610 | 0.84 | ADORA2A (0.64) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28413958 | 0.82 | ADORA2A (0.62) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28410735 | 0.81 | ADORA2A (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL28998309 | 0.79 | YTHDC1 (0.46) | YTHDC1ADORA2AADORA1ADORA2BADORA3 | |
| Hydrochloric Acid SCHEMBL9195525 | 0.76 | YTHDC1 (0.57) | YTHDC1ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL23771392 | 0.76 | YTHDC1 (0.66) | YTHDC1ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL763699 | 0.74 | YTHDC1 (1.00) | YTHDC1ADORA2AADORA1ADORA3PDE5A | |
| SCHEMBL28061333 | 0.74 | YTHDC1 (0.50) | YTHDC1ADORA2AADORA1ADORA2BPDE5A | |
| SCHEMBL22399501 | 0.73 | YTHDC1 (0.62) | YTHDC1ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL9120 | 0.73 | ADORA2A (0.59) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117778429-A | MMP20 gene mutant and application thereof | 华中科技大学同济医学院附属协和医院 | 2024-03-29 | — | — | CN | disclosed |