Succinic Acid Diethyl Ester

Succinic Acid Diethyl Ester

SCHEMBL29243135

CCCCCCC(CC)COC(=O)c1c(C(=O)O)ccc2ccccc12.CCOC(=O)CCC(=O)OCC

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.56
PRSS2 P07478 1/20 0.56
PRSS3 P35030 1/20 0.56
ALDH1A1 P00352 5/20 0.50
CYP3A4 P08684 3/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 3/20 0.47
TSHR P16473 2/20 0.43
MAPK1 P28482 2/20 0.43
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 1/20 0.39
TNF P01375 1/20 0.38
FAAH O00519 1/20 0.38
KDM4E B2RXH2 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CNR1 P21554 3/20 0.37
CNR2 P34972 3/20 0.37
TOP2A P11388 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29094249 0.93 PRSS1 (0.65) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL30558728 0.93 PRSS1 (0.65) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28888722 0.82 ALDH1A1 (0.70) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL29897693 0.78 PRSS1 (0.79) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL3764075 0.78 PRSS1 (0.70) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL11056026 0.77 CDC25B (0.55) ALDH1A1CA2LMNATSHRMAPK1
SCHEMBL3772079 0.77 PRSS1 (0.90) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL28117428 0.77 PRSS1 (0.90) PRSS1PRSS2PRSS3ALDH1A1CYP3A4
SCHEMBL10387424 0.77 ALDH1A1 (0.58) ALDH1A1CYP3A4LMNATSHRMAPK1
SCHEMBL10387044 0.75 TSHR (0.57) ALDH1A1CYP3A4LMNATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116634990-A Compositions comprising one or more (bio) -alkanediols with active ingredients 西姆莱斯股份公司 2023-08-22 CN disclosed