Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.70 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.70 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764072 | 0.89 | PRSS1 (0.77) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL28620299 | 0.87 | ALDH1A1 (0.73) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL3773194 | 0.86 | ALDH1A1 (0.50) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL3772079 | 0.86 | PRSS1 (0.90) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL28117428 | 0.86 | PRSS1 (0.90) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL6579655 | 0.85 | ALDH1A1 (0.73) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL28117745 | 0.84 | PRSS1 (0.87) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL30558728 | 0.83 | PRSS1 (0.65) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL29094249 | 0.83 | PRSS1 (0.65) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 | |
| SCHEMBL14377252 | 0.82 | PRSS1 (1.00) | PRSS1PRSS2PRSS3ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140228135-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT | KYODO YUSHI CO., LTD. (JP) | 2014-08-14 | — | — | US | disclosed |
| US-20100323934-A1 | GREASE COMPOSITION FOR CONSTANT VELOCITY JOINT AND CONSTANT VELOCITY JOINT | NTN CORPORATION (JP) | 2010-12-23 | — | — | US | disclosed |