Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 11/20 | 0.36 |
| ▸ | DRD3 | P35462 | 10/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756733 | 0.82 | MPO (0.44) | DRD2DRD3HTR1DCHRM1DRD4 | |
| SCHEMBL5847372 | 0.82 | MPO (0.44) | DRD2DRD3HTR1DCHRM1DRD4 | |
| SCHEMBL19132601 | 0.81 | ELANE (0.38) | ELANECA2DRD2DRD3HTR1D | |
| SCHEMBL22360909 | 0.80 | DRD2 (0.42) | CA2DRD2DRD3HTR1DCHRM1 | |
| SCHEMBL29756881 | 0.79 | ELANE (0.40) | ELANECA2HSD11B1 | |
| SCHEMBL20165338 | 0.79 | ELANE (0.40) | ELANECA2HSD11B1 | |
| SCHEMBL13392254 | 0.77 | ESR2 (0.42) | DRD2DRD3HTR1D | |
| SCHEMBL19616624 | 0.77 | METAP1 (0.37) | DRD2DRD3HTR1DHSD11B1CHRM1 | |
| SCHEMBL29631990 | 0.76 | MPO (0.37) | ELANECA2DRD2DRD3HTR1D | |
| SCHEMBL20211920 | 0.76 | MPO (0.37) | ELANECA2DRD2DRD3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118255703-A | Preparation method of estrogen receptor degradation agent | 南京医科大学 | 2024-06-28 | — | — | CN | disclosed |