Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21843465 | 0.84 | USP2 (0.49) | USP2SMN1; SMN2ACACBRECQLKDM4E | |
| SCHEMBL32683817 | 0.84 | USP2 (0.45) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL3223037 | 0.76 | AVPR1A (0.53) | NR1H2AVPR1AGPR119 | |
| SCHEMBL30008913 | 0.76 | AVPR1A (0.53) | NR1H2AVPR1AGPR119 | |
| SCHEMBL19693776 | 0.75 | USP2 (0.41) | USP2SMN1; SMN2NR1H2RECQLKDM4E | |
| SCHEMBL15507981 | 0.75 | ABHD6 (0.37) | USP2SMN1; SMN2NR1H2ACACBAVPR1A | |
| SCHEMBL15508223 | 0.75 | NR1H2 (0.35) | USP2SMN1; SMN2NR1H2ACACBAVPR1A | |
| SCHEMBL1489016 | 0.74 | USP2 (0.50) | USP2SMN1; SMN2NR1H2RECQLHPGD | |
| SCHEMBL23580046 | 0.73 | NR1H2 (0.55) | USP2SMN1; SMN2NR1H2KDM4EMAPT | |
| SCHEMBL8775525 | 0.73 | NR1H2 (0.48) | USP2SMN1; SMN2NR1H2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635380-A | PPARgamma modulators and methods of use | 卫材R&D管理有限公司 | 2023-08-22 | — | — | CN | disclosed |