Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082340 | 0.91 | HTT (0.61) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21082280 | 0.89 | MEN1 (0.64) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19899411 | 0.85 | HTT (0.59) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8102334 | 0.85 | HTT (0.59) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8106191 | 0.81 | HTT (0.70) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3357703 | 0.81 | HTT (0.73) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20382948 | 0.80 | HTT (0.68) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9511604 | 0.80 | HTT (0.58) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3358984 | 0.80 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30669320 | 0.80 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260162-B | 3-Hydroxy-4-pyridone-ciprofloxacin coupling, preparation method and application thereof | 浙江大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-115260162-A | 3-hydroxy-4-pyridone-ciprofloxacin coupling compound and preparation method and application thereof | 浙江大学 | 2022-11-01 | — | — | CN | disclosed |