Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21082340 | 0.87 | HTT (0.61) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29243860 | 0.85 | HTT (0.65) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8106191 | 0.84 | HTT (0.70) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20382948 | 0.83 | HTT (0.68) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3358984 | 0.83 | HTT (0.75) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL21082280 | 0.82 | MEN1 (0.64) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8133893 | 0.81 | KMT2A (0.47) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20382958 | 0.81 | HTT (0.71) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9515266 | 0.80 | HTT (0.67) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8122829 | 0.79 | HTT (0.73) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36831-E | TREATMENT OF IRON DEFICIENCY ANEMIA | BRITISH TECHNOLOGY GROUP LTD. (GB) | 2000-08-22 | — | — | US | disclosed |
| US-RE35948-E | TREATING TOXIC METAL CONCENTRATION BY ADMINISTERING N-SUBSTITUTED 3-HYDROXYPYRID-2-ONE OR 3-HYDROXYPYRID-4-ONE | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1998-11-03 | — | — | US | disclosed |
| EP-0305646-B1 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BRITISH TECH GROUP (GB) | 1996-11-13 | — | — | EP | disclosed |
| EP-0305646-A2 | 3-Hydroxypyrid-4-ones and pharmaceutical compositions | BTG INTERNATIONAL LIMITED (GB) | 1989-03-08 | — | — | EP | disclosed |
| EP-0120670-B1 | IRON III COMPLEXES OF HYDROXYPYRIDONES, AND THEIR PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1988-12-21 | — | — | EP | disclosed |
| US-4650793-A | NITROGEN-SUBSTITUTED | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-03-17 | — | — | US | disclosed |
| US-4585780-A | CHELATION OF HEAVY METALS IN BLOOD | NATIONAL RESEARCH DEVELOPMENT CORP. (GB) | 1986-04-29 | — | — | US | disclosed |
| EP-0120669-A2 | Hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |
| EP-0120670-A1 | Iron III complexes of hydroxypyridones, and their pharmaceutical compositions | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-10-03 | — | — | EP | disclosed |