SCHEMBL19899411

SCHEMBL19899411

C=C(C)C(=O)NCCn1ccc(=O)c(OCc2ccccc2)c1C

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 2/20 0.59
▸ SMN1; SMN2 Q16637 2/20 0.59
▸ MEN1 O00255 2/20 0.59
▸ KMT2A Q03164 2/20 0.59
▸ ALDH1A1 P00352 1/20 0.59
▸ HPGD P15428 1/20 0.59
▸ NPC1 O15118 1/20 0.55
▸ NPSR1 Q6W5P4 2/20 0.54
▸ MAOB P27338 3/20 0.46
▸ LMNA P02545 2/20 0.40
▸ MAPT P10636 1/20 0.40
▸ POLB P06746 1/20 0.39
▸ GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21082280 0.89 MEN1 (0.64) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL21082340 0.85 HTT (0.61) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL29243860 0.85 HTT (0.65) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL20382948 0.81 HTT (0.68) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL20382944 0.81 HTT (0.71) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL30669320 0.80 HTT (0.75) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL8106191 0.79 HTT (0.70) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL21046037 0.79 HTT (0.48) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL3357703 0.79 HTT (0.73) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL8102334 0.79 HTT (0.59) HTTSMN1; SMN2MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12024490-B2 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms for therapeutic use in treating diseases in animals, fish or humans CHELATION PARTNERS INCORPORATED (CA) 2024-07-02 — — US disclosed
US-20220002250-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS FOR THERAPEUTIC USE IN TREATING DISEASES IN ANIMALS, FISH OR HUMANS JUBILANT CHEMSYS LTD. (IN) 2022-01-06 — — US disclosed
US-20220002250-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS FOR THERAPEUTIC USE IN TREATING DISEASES IN ANIMALS, FISH OR HUMANS JUBILANT CHEMSYS LTD. (IN) 2022-01-06 — — US disclosed
US-11059785-B2 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms CHELATION PARTNERS INCORPORATED (CA) 2021-07-13 — — US disclosed
US-11059785-B2 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms CHELATION PARTNERS INCORPORATED (CA) 2021-07-13 — — US disclosed
EP-3504188-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS Chelation Partners Incorporated (CA) 2019-07-03 — — EP disclosed
US-20190169126-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS CHELATION PARTNERS INCORPORATED (CA) 2019-06-06 — — US disclosed
WO-2018035613-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS CHELATION PARTNERS INCORPORATED (CA) 2018-03-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002250-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS FOR THERAPEUTIC USE IN TREATING DISEASES IN ANIMALS, FISH OR HUMANS TFRC, HMBS, PICALM HTT 1484/4885SMN1; SMN2 812/4885MEN1 2264/4885
US-12024490-B2 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms for therapeutic use in treating diseases in animals, fish or humans TFRC, HMBS, PICALM HTT 1484/4885SMN1; SMN2 812/4885MEN1 2264/4885
US-11059785-B2 Polymeric metal chelating compositions and methods of preparing same for controlling growth and activities of living cells and organisms PICALM, HMBS, TFRC HTT 3362/4885SMN1; SMN2 2683/4885MEN1 1739/4885
US-20190169126-A1 POLYMERIC METAL CHELATING COMPOSITIONS AND METHODS OF PREPARING SAME FOR CONTROLLING GROWTH AND ACTIVITIES OF LIVING CELLS AND ORGANISMS PICALM, HMBS, TFRC HTT 3362/4885SMN1; SMN2 2683/4885MEN1 1739/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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