⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293604 | 0.93 | DGKA (0.65) | — | |
| SCHEMBL8379606 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL8379910 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL1003814 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL1003850 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL2892147 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL6163950 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL4452200 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL1001257 | 0.91 | DGKA (0.69) | — | |
| SCHEMBL6166366 | 0.91 | DGKA (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 407 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643059-A1 | 3-(3-Pyridinyl)-1H-indoles as thromboxane A2 synthetase inhibitors | Pfizer Limited (GB) | 1995-03-15 | — | — | EP | claimed |
| EP-0594588-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | Pfizer Limited (GB) | 1994-05-04 | — | — | EP | claimed |
| EP-0358398-B1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | Pfizer Limited (GB) | 1993-03-10 | — | — | EP | claimed |
| WO-1991013054-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE ANTIHYPERTENSIVE AGENTS | PFIZER LIMITED (GB) | 1991-09-05 | — | — | WO | claimed |
| EP-0358398-A1 | Cycloalkyl-substituted glutaramide antihypertensive agents | Pfizer Limited (GB) | 1990-03-14 | — | — | EP | claimed |
| US-4818754-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. OF BEECHAM HOUSE (GB) | 1989-04-04 | — | — | US | claimed |
| EP-0243055-A2 | Pyrazolopyridine derivatives, process for their preparation, and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1987-10-28 | — | — | EP | claimed |
| US-20240131180-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2024-04-25 | — | — | US | disclosed |
| EP-3546521-B1 | POLYCARBONATE RESIN COMPOSITION | MITSUBISHI ENG PLASTICS CORP (JP) | 2024-04-03 | — | — | EP | disclosed |
| EP-4025253-B1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR SA (ES) | 2024-03-20 | — | — | EP | disclosed |
| US-20230218774-A1 | DRUG ANTIBODY CONJUGATES | PHARMA MAR, S.A. (ES) | 2023-07-13 | — | — | US | disclosed |
| CN-113316564-B | Fused tricyclic deuterated derivative, and composition and application thereof | 四川海思科制药有限公司 | 2023-06-09 | — | — | CN | disclosed |
| WO-2023063154-A1 | TRACER COMPOSITION FOR RADIOACTIVE PET DIAGNOSIS, INTERMEDIATE THEREOF, AND PRODUCTION METHOD THEREOF | 国立大学法人大阪大学 | 2023-04-20 | — | — | WO | disclosed |
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |
| US-4393070-A | HYPOTENSIVE, VASODILATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-12 | — | — | US | disclosed |
| US-4373102-A | Isoindoline dyes, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1983-02-08 | — | — | US | disclosed |
| US-4307103-A | TREATMENT OF HYPERTENSION AND CARDIOVASCULAR DISEASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |
| EP-0017132-B1 | DYESTUFFS, THEIR PREPARATION AND UTILISATION | BASF Aktiengesellschaft (DE) | 1981-10-14 | — | — | EP | disclosed |
| EP-0017132-A1 | Dyestuffs, their preparation and utilisation | BASF Aktiengesellschaft (DE) | 1980-10-15 | — | — | EP | disclosed |
| US-4083684-A | AZO DYES, WASHFASTNESS, PHOTOSTABILITY, SOLVENT RESISTANCE | BASF AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |