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Sugi Predict / Targets / AIPL1

AIPL1

Aryl-hydrocarbon-interacting protein-like 1 · Q9NZN9 · AIPL1 on Sugi Atlas →

115 patent compounds predicted against AIPL1, 86 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL7003055 SCHEMBL7003055 0.74 1/20
SCHEMBL7002920 SCHEMBL7002920 0.70 1/20
SCHEMBL11324603 SCHEMBL11324603 0.66 1/20
SCHEMBL7003174 SCHEMBL7003174 0.62 1/20
SCHEMBL8277600 SCHEMBL8277600 0.62 1/20
SCHEMBL18180597 SCHEMBL18180597 0.62 1/20
SCHEMBL11332843 SCHEMBL11332843 0.60 1/20
SCHEMBL17817446 SCHEMBL17817446 0.60 1/20
SCHEMBL4091316 SCHEMBL4091316 0.57 1/20
SCHEMBL20831148 SCHEMBL20831148 0.57 1/20
SCHEMBL8004825 SCHEMBL8004825 0.56 1/20
SCHEMBL7005515 SCHEMBL7005515 0.55 1/20
SCHEMBL20831137 SCHEMBL20831137 0.55 1/20
SCHEMBL13126361 SCHEMBL13126361 0.54 1/20
SCHEMBL13126363 SCHEMBL13126363 0.54 1/20
SCHEMBL18177310 SCHEMBL18177310 0.54 1/20
SCHEMBL31060214 SCHEMBL31060214 0.54 1/20
SCHEMBL12952839 SCHEMBL12952839 0.54 1/20
SCHEMBL7003132 SCHEMBL7003132 0.54 1/20
SCHEMBL7669562 SCHEMBL7669562 0.53 1/20

Clinical trials — most relevant to AIPL1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study Evaluating Toxicity & Efficacy of Lenalidomide(Revlimid®)in Chemotherapy-Naïve AIPC Patients PHASE2COMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Epidemiology of Pituitary Tumours: Prevalence of Associated Neoplasia nanUNKNOWN
Aryl Hydrocarbon Receptor Interacting Protein (AIP) Gene Mutations in Acromegaly nanUNKNOWN
Elucidating the Molecular and Biochemical Basis of the Human AhR-mutation Disease nanUNKNOWN
Identification of Acute Intermittent Porphyria Modifying Genes nanRECRUITING
Observational Study of Acute Intermittent Porphyria Patients nanCOMPLETED
Molecular Epidemiology of Dioxin-Related Illness in Seveso nanCOMPLETED
The Role of Dietary Tryptophan on Aryl Hydrocarbon Receptor Activation nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Use of miRNAs in Growth Hormone Deficiency (GHD) nanUNKNOWN
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
Genetic Analysis for Predicting of Relapse During Steroid Treatment for Autoimmune Pancreatitis (AIP) nanCOMPLETED
Family Blood Pressure Program - GenNet Network nanCOMPLETED
Stress and Treatment Response in Puerto Rican Children With Asthma nanCOMPLETED
Involvement of Pollutants in Atopic Dermatitis and Psoriasis nanUNKNOWN
Towards an Easy-to-use Adrenal Cancer/Tumor Identity Card nanCOMPLETED
Genetic Studies of Inflammatory Bowel Disease nanCOMPLETED
Characterization of Microbiological and Genetic Features in Prostate Cancer and Their Association with Disease Stage nanENROLLING_BY_INVITATION
Family Blood Pressure Program - HyperGEN nanCOMPLETED
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Genetic Epidemiology of Asthma in Costa Rica nanCOMPLETED
Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus nanACTIVE_NOT_RECRUITING
Investigation of the Genetic Causes of Kallmann Syndrome and Reproductive Disorders nanCOMPLETED
Linkage Study in Familial Pulmonary Fibrosis nanCOMPLETED
Inherited Reproductive Disorders nanRECRUITING
Pituitary Derived-Intermedin is an Estrogen-Modulated Factor for Reducing Blood Pressure nanUNKNOWN
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
Genetic Markers as Predictors of Phenotypes in Pediatric Onset Crohn's Disease nanWITHDRAWN
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF) nanUNKNOWN

Related proteins — ESM-2 sequence neighbours (a AIPL1 binder may also engage these)

ProteinNameSimilarity
Q95MN9 — 1.000 Q95MN9 →
Q95MN8 — 1.000 Q95MN8 →
Q95MP0 — 1.000 Q95MP0 →
Q95MN7 — 1.000 Q95MN7 →
Q924K1 — 0.996 Q924K1 →
Q95MP1 — 0.995 Q95MP1 →
Q9JLG9 — 0.995 Q9JLG9 →
KDM5B Lysine-specific demethylase 5B 0.994 landscape →
KDM5D Lysine-specific demethylase 5D 0.993 landscape →
KAT8 Histone acetyltransferase KAT8 0.993 landscape →
Q9D5Z5 — 0.993 Q9D5Z5 →
Q5XUN4 — 0.992 Q5XUN4 →
Q5XI06 — 0.992 Q5XI06 →
A9JR78 — 0.992 A9JR78 →
Q9D3R6 — 0.992 Q9D3R6 →
DHX29 ATP-dependent RNA helicase DHX29 0.992 landscape →
O77775 — 0.992 O77775 →
AIP AH receptor-interacting protein 0.992 landscape →
Q6MG81 — 0.992 Q6MG81 →
Q5F3R2 — 0.992 Q5F3R2 →
O70145 — 0.991 O70145 →
P41230 — 0.991 P41230 →
Q8BJM7 — 0.991 Q8BJM7 →
A3KMI0 — 0.991 A3KMI0 →
Q62240 — 0.991 Q62240 →
KDM1A Lysine-specific histone demethylase 1A 0.991 landscape →
O97628 — 0.991 O97628 →
B7ZC32 — 0.991 B7ZC32 →
P25799 — 0.991 P25799 →
Q6IQX0 — 0.991 Q6IQX0 →