Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.50 |
| ▸ | RXRB | P28702 | 6/20 | 0.47 |
| ▸ | RXRG | P48443 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | RHEB | Q15382 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2999856 | 0.83 | AURKB (0.51) | IKBKBCHUKNUDT1POLBMAPT | |
| SCHEMBL29244612 | 0.78 | PRKCI (0.42) | IKBKBCHUKNUDT1 | |
| SCHEMBL31072687 | 0.76 | RXRA (0.56) | RXRARXRBRXRGHPGDMRGPRX4 | |
| SCHEMBL2310574 | 0.74 | NUDT1 (0.49) | IKBKBCHUKNUDT1 | |
| SCHEMBL29244676 | 0.74 | JAK1 (0.41) | HPGDSMN1; SMN2IKBKBCHUKMAPT | |
| SCHEMBL4791827 | 0.73 | IKBKB (0.76) | IKBKBCHUKNUDT1NEK1 | |
| SCHEMBL4365456 | 0.71 | AURKB (0.56) | IKBKBCHUK | |
| SCHEMBL2992617 | 0.70 | NUDT1 (0.55) | HPGDSMN1; SMN2IKBKBCHUKNUDT1 | |
| SCHEMBL367358 | 0.70 | MRGPRX4 (0.54) | RXRARXRBRXRGHPGDMRGPRX4 | |
| SCHEMBL27616079 | 0.70 | NUDT1 (0.51) | IKBKBCHUKNUDT1NEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239926-A | TLR7 and 8 inhibitors, preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |