Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29244669 | 0.84 | NPC1 (0.40) | NPC1NPSR1KDM4EMAPK1ATM | |
| SCHEMBL2176691 | 0.78 | LOXL2 (0.44) | LOXL2NPC1NPSR1KDM4EMAPK1 | |
| SCHEMBL29244609 | 0.77 | KAT2B (0.36) | NPC1NPSR1KDM4EMAPK1ATM | |
| SCHEMBL69407 | 0.76 | KDM4E (0.53) | NPC1NPSR1KDM4EMAPK1ATM | |
| SCHEMBL29244595 | 0.76 | NPC1 (0.48) | NPC1NPSR1KDM4EMAPK1ATM | |
| SCHEMBL31172759 | 0.75 | HDAC1 (0.41) | NPC1NPSR1KDM4EBRD4MAPT | |
| SCHEMBL16653480 | 0.75 | NPC1 (0.47) | NPC1NPSR1KDM4EMAPK1ATM | |
| SCHEMBL30935952 | 0.74 | LOXL2 (0.41) | LOXL2NPC1KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL8108945 | 0.72 | NPC1 (0.46) | NPC1NPSR1KDM4EMAPK1ATM | |
| SCHEMBL7860405 | 0.70 | NPC1 (0.47) | NPC1NPSR1KDM4EMAPK1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239926-A | TLR7 and 8 inhibitors, preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |