SCHEMBL2176691

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2175952	0.84	NPC1 (0.44)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL69407	0.80	KDM4E (0.53)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL29244643	0.78	LOXL2 (0.41)	LOXL2NPC1NPSR1KDM4EMAPK1
	SCHEMBL19434591	0.76	NPC1 (0.39)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL8108945	0.76	NPC1 (0.46)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL15564208	0.73	NPSR1 (0.51)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL13804468	0.73	NPC1 (0.47)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL12748885	0.73	NPC1 (0.47)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL7860405	0.73	NPC1 (0.47)	NPC1NPSR1KDM4EMAPK1ATM
	SCHEMBL29244595	0.73	NPC1 (0.48)	NPC1NPSR1KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.