Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | CA1 | P00915 | 6/20 | 0.71 |
| ▸ | CA2 | P00918 | 6/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13934091 | 0.89 | CA1 (0.87) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL5070309 | 0.87 | ALDH1A1 (1.00) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL12051728 | 0.83 | CA1 (1.00) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL17618029 | 0.83 | CA1 (0.77) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL12472851 | 0.83 | ALDH1A1 (0.74) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL64502 | 0.82 | ALDH1A1 (0.72) | ALDH1A1MAPTNPC1RAB9ACA1 | |
| SCHEMBL856237 | 0.82 | CA1 (0.70) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL15761719 | 0.82 | CA1 (0.75) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL16211427 | 0.82 | CA1 (0.75) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL11240016 | 0.82 | CA1 (0.75) | ALDH1A1MAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240398823-A1 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | TAIPEI MEDICAL UNIVERSITY (TW) | 2024-12-05 | — | — | US | disclosed |
| CN-118302401-A | Dual inhibitors of histone deacetylase 6 and heat shock protein 90 | 台北医学大学 | 2024-07-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240398823-A1 | DUAL INHIBITOR OF HISTONE DEACETYLASE 6 AND HEAT SHOCK PROTEIN 90 | HSP90AB1, HDAC6, HSP90AB2P | ALDH1A1 2299/4885MAPT 1544/4885NPC1 3070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.